Facial pain usually is similar to a headache but can be more intense and focused on the facial region. The pain may be centered on the mouth, on either side, or near the eyes or nose. In some cases, the pain may emanate from the jaw. Untreated facial pain can become a chronic condition. The level of pain may fluctuate from time to time. If the pain is caused by nerve damage, it can be piercing and you will not find relief without proper treatment.